Post Petraeus Scandal Google Releases Stats Showing Uptick in Gov Requests for Data



One day after news reports described the government’s surveillance of email accounts used for communication between the nation’s top spy and his mistress, Google released stats showing a rise in the number of U.S. government requests for data on Gmail users and their accounts.


The release of Google’s semi-annual Transparency Report, showing government requests for data for the first six months of this year, was never more relevant, following in the wake of reports that FBI investigators uncovered the affair between former CIA director David Petraeus and his biographer Paula Broadwell after gaining access to email accounts used by Broadwell.


According to the report, the United States’ demand for user data from Google continued to increase this year, with law enforcement agencies nationwide submitting requests 7,969 times for the first six months of the year, Google revealed Wednesday.


The jump, from 6,321 demands for data during the previous six-month period, covered 16,281 user accounts compared to 12,243 accounts from the company’s previous Transparency Report.


Google, which offers e-mail, cloud storage, a blogging platform, web search, and other services, has released a Transparency Report every six months since 2009. The reports provide information on requests for data from governments around the world, as well as on takedown requests submitted to Google’s various services for suspected copyright infringement, defamation and other reasons.


Of the 31 nation’s surveyed, the U.S. led the pack in requests for user data. India came in second with 2,319 requests for data on 3,467 accounts. The United Kingdom, Brazil, France and Germany each made roughly 1,500 requests.


Overall globally, the number of requests have skyrocketed from 12,539 at the end of 2009, when Google first began producing the reports, to 20,938 in the latest reporting period.


“This is the sixth time we’ve released this data, and one trend has become clear: Government surveillance is on the rise,” Google said in a statement.


In addition to the statistics Google released on government data and takedown requests, the search giant also released figures showing the number of times it has acquiesced to court orders to remove content from its search results, YouTube and other products and services. The bulk of these requests stemmed from disputes surrounding issues of trademark and defamation.


The U.S. also led the way in these requests, with a 46 percent increase from the prior six months. The company said that during the first half of this year, it removed 1,664 Google Groups posts for defamation reasons, 641 search results for the same reason and 156 search results for trademark violations — all in response to court orders.


Google’s transparency data is limited, as it does not include requests submitted under the Patriot Act, which can include National Security Letters that come with gag orders attached to them. Nor does the data include anti-terrorism eavesdropping court orders, known as FISA orders, or any dragnet surveillance programs legalized in 2008, as those are secret, too.


The data Google hands over to governments can include e-mail communications, documents, browsing activity and IP addresses used to create and access an account, among other things.


According to news reports, investigators obtained access to email accounts that Broadwell used, including a Gmail account she used to communicate with Petraeus, after examining the header information of harassing emails she allegedly sent to a woman in Florida.


Investigators were able to match the locations from which the e-mails were sent to the same locations, including hotels, where Broadwell was known to have been during the times the correspondence was sent. Based on these connections, investigators obtained a warrant to monitor other e-mail accounts Broadwell used, including the Gmail account.


While Google has become increasingly more transparent in providing these numbers, the company’s reports contain a glaring omission. Nowhere do they indicate how many times the company actually turned over user data in the U.S. as a result of probable-cause warrants it received requesting data.


Google on Tuesday declined to provide that figure or respond to questions about why it does not disclose the information. The company also will not say how often it turns over data without a probable-cause warrant, which it can do, since U.S. law does not always require a warrant for such data.


The 1986 Electronic Communications Privacy Act currently allows the government to acquire a suspect’s e-mail or other stored content from an internet service provider without showing probable cause that a crime was committed, as long as the content has been stored on a third-party server for 180 days or more. Under ECPA, the government only needs to show that it has “reasonable grounds to believe” the information would be useful in an investigation.


Senate Judiciary Committee chairman Patrick Leahy (D-Vermont) on Thursday is attempting to remedy this by pushing an amendment through his committee that would offer sweeping digital privacy protections by requiring the government, for the first time, to get a probable-cause warrant to obtain e-mail and other content stored in the cloud.


ECPA was adopted at a time when digital storage of content was expensive and e-mail wasn’t stored on servers for long periods of time. In the 1980s, e-mail more than 6 months old was assumed abandoned, and therefore ripe for the taking without a probable-cause warrant. As storage capacities have increased and become cheaper, users are storing more content for indefinite periods.



Read More..

Charlie Chaplin’s bowler and cane to hit auction block
















LOS ANGELES (Reuters) – One of Charlie Chaplin’s iconic bowler hats and canes, the staple of Hollywood silent-era comedy, will go under the hammer in Los Angeles this weekend, auction house Bonhams said on Tuesday.


Chaplin’s hat and cane – synonymous with his trademark “Little Tramp” character in films such as “City Lights” and “Modern Times” – are expected to fetch between $ 40,000 and $ 60,000 in the November 18 auction.













It is unknown how many of Chaplin’s bowlers and canes still exist, said Lucy Carr, a memorabilia specialist at Bonhams. The ones up for auction come from a private collection but have a direct link to Chaplin, Carr said.


The waddling and bumbling Little Tramp character propelled Chaplin to global fame. The character, which Hollywood legend says was created by accident on a rainy day at Keystone Studio, first appeared in 1914′s “Kid Auto Races at Venice” and lastly in 1936′s “Modern Times.”


Chaplin’s hat and cane are the highlights of an auction of popular culture artifacts including a saxophone that belonged to jazz pioneer Charlie Parker ($ 22,000-$ 26,000) and a handwritten letter from John Lennon in which The Beatle sketched himself and wife Yoko Ono nude ($ 18,000-$ 22,000).


Other items hitting the block range from an archive of Marilyn Monroe photographs ($ 15,000-$ 20,000), an early Charles Schulz “Peanuts” comic strip ($ 10,000-$ 15,000) and a wicker chair from Rick’s Cafe in “Casablanca” ($ 5,000-$ 7,000).


(Reporting By Eric Kelsey, editing by Jill Serjeant)


Celebrity News Headlines – Yahoo! News



Read More..

‘Dream Team’ of Behavioral Scientists Advised Obama Campaign


Chris Keane/Reuters


DOOR TO DOOR Ricky Hall, an Obama volunteer, in Charlotte, N.C., last week.







Late last year Matthew Barzun, an official with the Obama campaign, called Craig Fox, a psychologist in Los Angeles, and invited him to a political planning meeting in Chicago, according to two people who attended the session.




“He said, ‘Bring the whole group; let’s hear what you have to say,’ ” recalled Dr. Fox, a behavioral economist at the University of California, Los Angeles.


So began an effort by a team of social scientists to help their favored candidate in the 2012 presidential election. Some members of the team had consulted with the Obama campaign in the 2008 cycle, but the meeting in January signaled a different direction.


“The culture of the campaign had changed,” Dr. Fox said. “Before then I felt like we had to sell ourselves; this time there was a real hunger for our ideas.”


This election season the Obama campaign won a reputation for drawing on the tools of social science. The book “The Victory Lab,” by Sasha Issenberg, and news reports have portrayed an operation that ran its own experiment and, among other efforts, consulted with the Analyst Institute, a Washington voter research group established in 2007 by union officials and their allies to help Democratic candidates.


Less well known is that the Obama campaign also had a panel of unpaid academic advisers. The group — which calls itself the “consortium of behavioral scientists,” or COBS — provided ideas on how to counter false rumors, like one that President Obama is a Muslim. It suggested how to characterize the Republican opponent, Mitt Romney, in advertisements. It also delivered research-based advice on how to mobilize voters.


“In the way it used research, this was a campaign like no other,” said Todd Rogers, a psychologist at Harvard’s Kennedy School of Government and a former director of the Analyst Institute. “It’s a big change for a culture that historically has relied on consultants, experts and gurulike intuition.”


When asked about the outside psychologists, the Obama campaign would neither confirm nor deny a relationship with them. “This campaign was built on the energy, enthusiasm and ingenuity of thousands of grass-roots supporters and our staff in the states and in Chicago,” said Adam Fetcher, a campaign spokesman. “Throughout the campaign we saw an outpouring of individuals across the country who lent a wide variety of ideas and input to our efforts to get the president re-elected.”


For their part, consortium members said they did nothing more than pass on research-based ideas, in e-mails and conference calls. They said they could talk only in general terms about the research, because they had signed nondisclosure agreements with the campaign.


In addition to Dr. Fox, the consortium included Susan T. Fiske of Princeton University; Samuel L. Popkin of the University of California, San Diego; Robert Cialdini, a professor emeritus at Arizona State University; Richard H. Thaler, a professor of behavioral science and economics at the University of Chicago’s business school; and Michael Morris, a psychologist at Columbia.


“A kind of dream team, in my opinion,” Dr. Fox said.


He said that the ideas the team proposed were “little things that can make a difference” in people’s behavior.


For example, Dr. Fiske’s research has shown that when deciding on a candidate, people generally focus on two elements: competence and warmth. “A candidate wants to make sure to score high on both dimensions,” Dr. Fiske said in an interview. “You can’t just run on the idea that everyone wants to have a beer with you; some people care a whole lot about competence.”


Mr. Romney was recognized as a competent businessman, polling found. But he was often portrayed in opposition ads as distant, unable to relate to the problems of ordinary people.


When it comes to countering rumors, psychologists have found that the best strategy is not to deny the charge (“I am not a flip-flopper”) but to affirm a competing notion. “The denial works in the short term; but in the long term people remember only the association, like ‘Obama and Muslim,’ ” said Dr. Fox, of the persistent false rumor.


The president’s team affirmed that he is a Christian.


At least some of the consortium’s proposals seemed to have found their way into daily operations. Campaign volunteers who knocked on doors last week in swing states like Pennsylvania, Ohio and Nevada did not merely remind people to vote and arrange for rides to the polls. Rather, they worked from a script, using subtle motivational techniques that research has shown can prompt people to take action.


“We used the scripts more as a guide,” said Sarah Weinstein, 18, a Columbia freshman who traveled with a group to Cleveland the weekend before the election. “The actual language we used was invested in the individual person.”


This article has been revised to reflect the following correction:

Correction: November 13, 2012

An earlier version of this article omitted a word from the title of the book by Sasha Issenberg that examines data-driven strategies in political campaigns. It is “The Victory Lab,”  not “Victory Lab.”



Read More..

I.H.T. Special Report | Oil & Money: After Years of Waiting, Virginia Wants to Make Its Name in Oil


Jason Hirschfeld/Associated Press


Hurricane Sandy pounding the coastline last month in Virginia Beach, Va. The state is the new epicenter of efforts by energy companies to get a toehold in the potentially vast resources hidden beneath the Atlantic.










WASHINGTON — When Doug Domenech looks out at the Atlantic Ocean, he sees oil and natural gas and jobs and revenue. Standing between him and those prizes are President Barack Obama, the U.S. Navy and the whales.




Mr. Domenech, Virginia’s secretary of natural resources, is undeterred. He and the state’s Republican governor, Bob McDonnell, have teamed up with Virginia’s two Democratic senators to try to do a run around the president and put Virginia’s coast on the energy map through an act of Congress.


The state is making efforts to restore a lease sale for energy exploration that was canceled in 2010 after the oil spill in the Gulf of Mexico followed an explosion on a drilling rig that was connected to a well owned by BP. The efforts have made Virginia the new epicenter of efforts by energy companies to get a toehold in the potentially vast resources hidden beneath the Atlantic.


“The administration not only took away our sale, but they didn’t reinstate it into the next five-year plan. They booted us off to 2017,” Mr. Domenech said. “That’s what made us start pursuing other avenues in Congress.”


Oil companies and government officials believe there is oil and natural gas off the East Coast of the United States. Exploration, however, has been blocked for more than 30 years after a devastating spill off the coast of California turned public opinion against offshore drilling.


That political environment changed in the past decade as oil prices soared and the American public and politicians weighed their fears of offshore drilling against the geopolitical threat of being dependent on oil from hostile nations or unstable regions.


Now seven companies, including Houston-based Global Geo Services and Western Geco, a subsidiary of Schlumberger, have applied for permission to conduct seismic studies along the East Coast from New Jersey all the way to Florida. Efforts are focusing on Virginia because the public, politicians in both parties and energy companies all favor opening the waters to drilling.


To proceed, the would-be explorers will need to bypass the vocal opposition of advocates who say that even the preliminary survey work would harm endangered whales and the U.S. Navy, which uses the waters off Virginia as training grounds for its Norfolk base.


“It’s an important frontier, and it’s right next to a large market,” said Joe Gagliardi, vice president of marine programs at Ion Geophysical Corp., a Houston-based company that has applied to spend six months conducting two-dimensional seismic surveys from New Jersey to Florida. “The Eastern seaboard market is huge.”


The Bureau of Ocean Energy Management estimates that there are 3.3 billion barrels of recoverable oil on the Atlantic’s outer continental shelf and another 31.3 trillion cubic feet, or 886.3 million cubic meters, of natural gas. The estimates are based on two-dimensional seismic surveys that were done in the early 1980s.


While they are careful to say that they have no idea what energy resources might be hidden beneath the Atlantic, energy industry executives believe that the B.O.E.M.’s estimates are low, noting the industry's history in the Gulf of Mexico..


“Initial estimates in the Gulf were five billion barrels of oil,” said Andy Radford, senior policy adviser at the American Petroleum Institute. “We’ve already produced over 20 billion, and current estimates are that there are 48 billion more.”


There are other indicators that drilling there could lead to big discoveries.


“We know there are oil seeps all along the East Coast of the U.S.,” Mr. Gagliardi said. “Naturally the earth is leaking oil on a daily basis. There’s a natural petroleum system out there.”


The Eastern Seaboard of the United States was once connected to the coast of West Africa before the continent split in two and the pieces drifted apart, creating the Atlantic Ocean. Nigeria alone has more than 37 billion barrels of proven reserves, much of it off the coast in deep water.


Tullow Oil, a company working on the same theory, struck oil last year off the coast of French Guiana. The company, which is London-based, said it had begun exploring in the area because it believed the geology mirrored its earlier successful discoveries across the ocean off the coast of West Africa.


Read More..

Newton: Jan Perry's path to power








An essential element of a successful political campaign, whether for U.S. president or mayor of Los Angeles, is that it identifies a path to victory. Candidates have to differentiate themselves from competitors and appeal to constituencies sympathetic to their message.

At this point in the Los Angeles mayor's race, Councilwoman Jan Perry lags behind front-runners Wendy Greuel and Eric Garcetti in terms of money and name recognition, but in recent weeks she has found a potentially viable path.

Perry's approach reflects an important feature of the field for this campaign: Controller Greuel and Councilman Garcetti, the leading candidates at this early stage, bring to the campaign virtually identical politics and similar temperaments. Both are personable, smart liberals with strong ties to organized labor. Greuel draws support from the International Brotherhood of Electrical Workers, the union that represents employees of the Los Angeles Department of Water and Power, while Garcetti is close to the Service Employees International Union, which represents some city and county workers and others in service industries.






Those relationships are likely to supply Garcetti and Greuel with volunteers and financial support, both vital to winning. But they also present Perry with an opportunity to set herself apart. Now that County Supervisor Zev Yaroslavsky and businessmen Austin Beutner and Rick Caruso have opted out of the campaign, Perry finds herself with a surprisingly open shot at becoming the favored candidate of business. As one longtime observer of this region's politics remarked to me last week, "It's the only way for her to go."

Last week, Perry demonstrated that she's gotten that message. Speaking to a small but welcoming audience at the Japanese American National Museum, Perry staked out her territory. She said she would oppose increases in sales and documentary transfer taxes — proposals that may appear on the same ballot as the mayoral contest's first round in March. She argued for offloading some city assets, such as the Convention Center and zoo. And she insisted that the city's budget problems — it faces a shortfall of more than $200 million this year, and the prognosis gets worse looking ahead — need to be addressed by asking city employees to contribute more to their medical coverage and pensions. That's just what business wants to hear.

"I am a lifelong Democrat who is a business-friendly Democrat," she said. By contrast, she said, her chief opponents will find it difficult to challenge City Hall's status quo in areas such as rate increases and pension reform. "I think they both will have obligations that they will have to meet, one to IBEW, the other to SEIU."

There is a fourth candidate who could plant his flag in this same area. Lawyer and radio personality Kevin James is campaigning at the race's only true outsider. The same calculations that have raised Perry's possibilities have increased his as well, but she has experience and credentials that will make it hard for him to head her off.

Perry is likable, with a refreshing candor. Last week, she slipped off her shoes as she delivered her speech and took questions from reporters until they had no more. And she didn't exaggerate what is achievable: Asked whether she thought the city could rebound over the next four years, she said, basically, no.

But she has liabilities too. In 2007, she joined council colleagues — including Greuel and Garcetti — in voting for a salary increase that gave city workers more than 25% over five years. The deal was rendered insupportable when the economy tanked the next year, but it doesn't take a Nobel laureate to see that not many workers in 2007 were getting deals that promised them annual salary increases of 5%. When I asked her if she regretted that vote, Perry laughed. "Yes," she said. "Of course."

Perry does have her share of enemies. She is famously stubborn — one joke kicking around the campaign is that she might have dropped out of this race and instead run for controller if only so many people hadn't asked her to. And the demographic dynamics of her base are complicated. She's African American and enjoys strong support from that important but relatively small community. She's also, unbeknownst to many voters, Jewish, which supplies her either with a way to extend her base or to confuse it.

The business elites that supported Richard Riordan in the 1990s had hoped Beutner would run, and they have yet to fall in behind Perry. But they're without a standard-bearer at the moment, and that could leave Perry with a powerful constituency, a coherent message — and a path.

Jim Newton’s column appears Mondays. His latest book is "Eisenhower: The White House Years." Reach him at jim.newton@latimes.com or follow him on Twitter: @newton_jim.






Read More..

Early, Facehugger-Filled <em>Prometheus</em> Script Leaks Online



For a movie set in Ridley Scott’s Alien universe, this summer’s Prometheus was relatively low on, well, aliens. But an earlier draft of the script, recently leaked online, has many more — including facehuggers.


The script — for a film at the time called Alien: Engineers — appears to be one of the earlier versions of the story penned by Jon Spaihts, before Lost scribe Damon Lindelof took it over. Spaihts appears to have confirmed that the script is real on Twitter, responding to a question about the uploaded document with terse tweet: “That’s authentic.” The script also appears to include many plot points the writer has said were in his original drafts.


(Spoiler alert: Major Prometheus plot points follow.)



Around the time of Prometheus’ release on Blu-ray, Spaihts told Empire magazine that he had written a slightly different — though just as traumatic — Med Pod scene involving Elizabeth Shaw (the character ultimately played by Noomi Rapace and named “Jocelyn Watts” in the leaked script) going into a medical pod to have an alien parasite removed from her abdomen. In the film version, Shaw escapes the pod following the surgery, leaving the creature behind. In Spaihts’ script, the parasite escapes and becomes monstrous, leaving Shaw, er Watts, trapped inside.


“By the time she emerges from the pod eight hours later, the thing is abroad in the ship and big enough to be a huge danger. That was the original conception of the med pod scene,” Spaihts told Empire. “My script underwent a number of major evolutions as we were working on it, and then Damon came in and made further changes still. But that sequence and its place in the story was one of the anchors.”


What’s very different in the leaked version of the script is how the alien parasites found their way into not only Shaw/Watts but also her partner, Charlie Holloway (named “Martin Holloway” in the script and played by Logan Marshall-Green in the movie). In the film, the android David (played by Michael Fassbender) exposes Holloway to the creature through a drop of mysterious black goo. In the early version of the script, David actually coaxes a facehugger — a facehugger! — out of an egg and places it on Shaw/Watts.


“I’m not what it wants. But you, with your warm wet breath… It knows you,” the droid says in the script, aware he is in no way a worthy host. Holloway, however, gets facehugged in the early script while the team is investigating the Engineers and has a chestburster moment — chestburster! — during sex with Watts. (Seriously, read it. It’s all as nuts as it sounds.)


And that’s just the beginning. Check out the whole crazy script below or download it here. Let us know in the comments what you think about the early script and how you think it stacks up to Scott’s film.


[via Bloody Disgusting]


Alien Engineers


Read More..

U2′s Bono to urge U.S. politicians not to cut aid programs
















WASHINGTON (Reuters) – Irish rocker and anti-poverty campaigner Bono will appeal to Democrats and Republicans during a visit to Washington this week to spare U.S. development assistance programs from cuts as Congress tries to avert the looming “fiscal cliff” of tax hikes and spending reductions early next year.


The U2 lead singer’s visit comes as the Obama administration and congressional leaders try to forge a deal in coming weeks to avoid the economy hitting the “fiscal cliff” – tax increases and spending cuts worth $ 600 billion starting in January if Congress does not act.













Analysts say the absence of a deal could shock the United States, the world’s biggest economy, back into recession.


Kathy McKiernan, spokeswoman for the ONE Campaign, said Bono will hold talks with congressional lawmakers and senior Obama administration officials during the November 12-14 visit.


During meetings he will stress the effectiveness of U.S. foreign assistance programs and the need to preserve them to avoid putting at risk progress made in fighting HIV/AIDS, tuberculosis and malaria, she said.


Bono, a long-time advocate for the poor, will argue that U.S. government-funded schemes that support life-saving treatments for HIV/AIDS sufferers, nutrition programs for malnourished children, and emergency food aid make up just 1 percent of the U.S. government budget but are helping to save tens of millions of lives in impoverished nations.


The One Campaign would not elaborate which lawmakers and senior Obama administration officials Bono will meet.


On Monday, Bono will discuss the power of social movements with students at Georgetown University. He will also meet new World Bank President Jim Yong Kim for a web cast discussion on Wednesday on the challenges of eradicating poverty.


(Editing by W Simon)


Music News Headlines – Yahoo! News



Read More..

Alzheimer’s Precursors Founds at Earlier Age





Scientists studying Alzheimer’s disease are increasingly finding clues that the brain begins to deteriorate years before a person shows symptoms of dementia.




Now, research on a large extended family of 5,000 people in Colombia with a genetically driven form of Alzheimer’s has found evidence that the precursors of the disease begin even earlier than previously thought, and that this early brain deterioration occurs in more ways than has been documented before.


The studies, published this month in the journal Lancet Neurology, found that the brains of people destined to develop Alzheimer’s clearly show changes at least 20 years before they have any cognitive impairment. In the Colombian family, researchers saw these changes in people ages 18 to 26; on average, members of this family develop symptoms of mild cognitive impairment at 45 and of dementia at 53.


These brain changes occur earlier than the first signs of plaques made from a protein called beta amyloid or a-beta, a hallmark of Alzheimer’s. Researchers detected higher-than-normal levels of amyloid in the spinal fluid of these young adults. They found suggestions that memory-encoding parts of the brain were already working harder than in normal brains. And they identified indications that brain areas known to be affected by Alzheimer’s may be smaller than in those who do not have the Alzheimer’s gene.


“This is one of the most important pieces of direct evidence that individual persons have the disease and all the pathology many years before,” said Dr. Kaj Blennow, a professor in clinical neurochemistry at the University of Gothenburg in Sweden, who was not involved in the research.


Dr. Nick Fox, a neurologist at University College London, who was also not part of the research, said the findings suggested that “some of the things that we thought were more downstream may not be quite so downstream; they may be happening earlier.”


That, in turn, said Dr. Fox, who wrote a commentary about the findings in Lancet Neurology, could have implications for when and how to treat people, because “there may be targets to attack, whether it’s high levels of a-beta or whatever, when people are still functioning very well.”


The Colombian family suffers from a rare form of Alzheimer’s that is caused by a genetic mutation; it strikes about a third of its members in midlife. Because the family is so large and researchers can identify who will get the disease, studying the family provides an unusual opportunity to learn about Alzheimer’s causes and pathology.


Researchers, led by Dr. Eric Reiman of the Banner Alzheimer’s Institute in Phoenix, and in Colombia by Dr. Francisco Lopera, a neurologist at the University of Antioquia, recently received a grant from the National Institutes of Health to conduct a clinical trial to test a drug on family members before they develop symptoms, to see if early brain changes can be halted or slowed.


The studies in Lancet Neurology used several tests, including spinal taps, brain imaging and functional M.R.I.


“The prevailing theory has been that development of Alzheimer’s disease begins with the progressive accumulation of amyloid in the brain,” Dr. Reiman said. “This study suggests there are changes that are occurring before amyloid deposition.”


One possibility is that brain areas are already impaired. Another possibility, experts said, is that these brain differences may go back to the young developing brain.


“It is a genetic disease, and it’s not hard to imagine that your gene results in some differences in the way your brain is formed,” said Dr. Adam Fleisher, director of brain imaging at the Banner Institute and an author of the studies.


In one of the Lancet Neurology studies, researchers examined 44 relatives between ages 18 to 26. Twenty had the mutation that causes Alzheimer’s. The cerebrospinal fluid of those with the mutation contained more amyloid than that of relatives without it. This was striking because researchers know that when people develop amyloid plaques — whether they have early-onset or late-onset Alzheimer’s — amyloid levels in their spinal fluid are lower than normal. That is believed to be because the fluid form of amyloid gets absorbed into the plaque form, Dr. Reiman said.


So, the high level of amyloid fluid in the Colombian family supports a hypothesis about a difference between the beginning phases of genetic early-onset Alzheimer’s and the more common late-onset Alzheimer’s. The difference may be that early-onset Alzheimer’s involves an overproduction of amyloid, while late onset involves a problem clearing amyloid from the brain.


In another result, when the subjects performed a task matching names with faces, those with the mutation had greater activity in the hippocampus and parahippocampus, areas involved in memory. Dr. Reiman suggested this could mean that the pre-Alzheimer’s brain has to expend more effort to encode memories than a normal brain.


Researchers also found that the mutation carriers had less gray matter in areas that tend to shrink when people develop dementia. Dr. Fox emphasized that seeing less gray matter so early was so novel that it should be treated cautiously unless other studies find a similar result.


In the second study, brain imaging was used to look for amyloid plaques in 50 people ages 20 to 56: 11 with dementia, 19 mutation carriers without symptoms and 20 normal family members. Plaques occurred at an average age of 28, more than 15 years before cognitive impairment would be expected and two decades before dementia.


The study also found that amyloid plaques increased steadily until about age 37, after which the brain did not seem to gain many more plaques. Dr. Blennow said that while researchers know that amyloid plaques plateau when people already have dementia, they did not know that the plateau appears to occur years before.


The researchers are currently analyzing data from family members ages 7 to 17 to see if some of the brain changes occur at an even younger age.


“Some people think that that may be scary, that you can see it so many years before,” Dr. Reiman said. “But it seems to me that that provides potential opportunities for the development of future therapies.”


Read More..

Report Sees U.S. as Top Oil Producer, Overtaking Saudi Arabia, in 5 Years


Charlie Riedel/Associated Press


A pump jack near Greensburg, Kan. Increased oil production and new policies to improve energy efficiency mean that the United States will become “all but self-sufficient” in energy in about two decades, the International Energy Agency predicted.







The United States will overtake Saudi Arabia as the world’s leading oil producer by about 2017 and will become a net oil exporter by 2030, according to a new report released on Monday by the International Energy Agency.




That increased oil production, combined with new American policies to improve energy efficiency, means that the United States will become “all but self-sufficient” in meeting its energy needs in about two decades — a “dramatic reversal of the trend” in most developed countries, the report says.


“The foundations of the global energy systems are shifting,” said Fatih Birol, chief economist at the Paris-based organization, which produces the annual World Energy Outlook, in an interview before the release. The agency, which advises industrialized nations on energy issues, had previously predicted that Saudi Arabia would be the leading producer until 2035.


The report also predicted that global energy demand would grow by 35 percent to 46 percent between 2010 and 2035, depending on whether policies that have been proposed are actually put in place. Most of that growth will come from China, India and the Middle East, where the consuming class is growing rapidly. The consequences are “potentially far reaching” for global energy markets and trade, the report said.


Dr. Birol noted, for example, that Middle Eastern oil once bound for the United States would probably be rerouted to China. American-mined coal, facing declining demand in its home market, is already heading to Europe and China instead.


There are several components of the sudden shift in the world’s energy supply, but the prime mover is a resurgence of oil and gas production in the United States, particularly the unlocking of new reserves of oil and gas found in shale rock. The widespread adoption of techniques such as hydraulic fracturing and horizontal drilling has made those reserves much more accessible, and in the case of natural gas, resulted in a vast glut that has sent prices plunging.


The report predicted that the United States would overtake Russia as the leading producer of natural gas in 2015.


The strong statements and specific predictions by the energy agency lend new weight to trends that have become increasingly apparent in the last year.


“This striking conclusion confirms a lot of recent projections,” said Michael Levi, senior fellow for energy and environment at the Council on Foreign Relations.


Formed in 1974 after the oil crisis by a group of oil-importing nations, including the United States, the International Energy Agency monitors and analyzes global energy trends to insure safe and sustainable supply.


Mr. Levi said that the I.E.A. report was generally “good news” for the United States because it highlights the nation’s new sources of energy. But he cautioned that being self-sufficient did not mean that the country would be insulated from seesawing energy prices, since those oil prices are set by global markets.


“You may be somewhat less vulnerable to price shocks and the U.S. may be slightly more protected, but it doesn’t give you the energy independence some people claim,” he said.


Also, he noted, the agency’s projection of United States self-sufficiency assumed that the country would push ahead with improving gas mileage in cars and energy efficiency in homes and appliances. “It’s supply and demand together that adds up to this striking conclusion,” Mr. Levi said.


Dr. Birol said the agency’s prediction of increasing American self-sufficiency was 55 percent a reflection of more oil production and 45 percent a reflection of improving energy efficiency in the United States, primarily from the Obama administration’s new fuel economy standards for cars. He added that even stronger policies to promote energy efficiency were needed in the United States and many other countries.


The report said that several other factors could also have a large impact on world energy markets over the next few years. These include the recovery of the Iraqi oil industry, which would lead to new supply, and the decision by some countries, notably Germany and Japan, to move away from nuclear energy in the wake of the Fukushima disaster.


The new energy sources will help the United States economy, Dr. Birol said, providing continued cheap energy relative to the rest of the world. The I.E.A. estimates that electricity prices will be about 50 percent cheaper in the United States than in Europe, largely because of a rise in the number of power plants fueled by cheap natural gas, helping American industries and consumers.


But the message is more sobering for the planet, in terms of climate change. Although natural gas is frequently promoted for being relatively low in carbon emissions compared to oil or coal, the new global energy market could make it even harder to prevent dangerous levels of warming.


The United States’ reduced reliance on coal will just mean that coal moves to other places, the report says. And the use of coal, now the dirtiest fuel, continues to rise elsewhere. China’s coal demand will peak around 2020 and then stay steady until 2035, the report predicted, and in 2025, India will overtake the United States as the world’s second-largest coal user.


The report warns that no more than one-third of the proven reserves of fossil fuels should be used by 2050 to limit global warming to 2 degrees Celsius, as many scientists recommend.


Such restraint is extremely unlikely without a binding international treaty by 2017 that requires countries to limit the growth of their emissions, Dr. Birol said. He added that pushing ahead with technologies that could capture and store carbon dioxide was also crucial.


“The report confirms that, given the current policies, we will blow past every safe target for emissions,” Mr. Levi said. “This should put to rest the idea that the boom in natural gas will save us from that.”


This article has been revised to reflect the following correction:

Correction: November 12, 2012

An earlier version of this article misstated the International Energy Agency’s prediction of American self-sufficiency in energy production. The agency said 55 percent of the improvement would come from more oil production and 45 percent from improvements in energy efficiency. It did not say that domestic oil production would rise 55 percent. Also, an earlier version of a photo caption with this article misidentified the equipment shown in use in an oil field in Greensburg, Kan. It is a pump jack, not an oil rig.



Read More..

Times investigation: Legal drugs, deadly outcomes









Terry Smith collapsed face-down in a pool of his own vomit.

Lynn Blunt snored loudly as her lungs slowly filled with fluid.

Summer Ann Burdette was midway through a pear when she stopped breathing.





Larry Carmichael knocked over a lamp as he fell to the floor.

Jennifer Thurber was curled up in bed, pale and still, when her father found her.

Karl Finnila sat down on a curb to rest and never got up.

These six people died of drug overdoses within a span of 18 months.

But according to coroners' records, that was not all they had in common. Bottles of prescription medications found at the scene of each death bore the name of the same doctor: Van H. Vu.

After Finnila died, coroner's investigators called Vu to learn about his patient's medical history and why he had given him prescriptions for powerful medications, including the painkiller hydrocodone.

Investigators left half a dozen messages. Vu never called back, coroner's records state.

Over the next four years, 10 more of his patients died of overdoses, the records show. In nine of those cases, painkillers Vu had prescribed for them were found at the scene.

Vu, a pain specialist in Huntington Beach, described himself as a conscientious, caring physician. He declined to comment on individual cases, citing confidentiality laws, but he said he treats many "very, very difficult patients" whose chronic pain is sometimes complicated by substance abuse and depression, anxiety or other mental illness.

"Every single day, I try to do the best I can for every single patient," he said in an interview. "I can't control what they do once they leave my office."

Prescription drug overdoses now claim more lives than heroin and cocaine combined, fueling a doubling of drug-related deaths in the United States over the last decade.

Health and law enforcement officials seeking to curb the epidemic have focused on how OxyContin, Vicodin, Xanax and other potent pain and anxiety medications are obtained illegally, such as through pharmacy robberies or when teenagers raid their parents' medicine cabinets. Authorities have failed to recognize how often people overdose on medications prescribed for them by their doctors.

A Los Angeles Times investigation has found that in nearly half of the accidental deaths from prescription drugs in four Southern California counties, the deceased had a doctor's prescription for at least one drug that caused or contributed to the death.

Reporters identified a total of 3,733 deaths from prescription drugs from 2006 through 2011 in Los Angeles, Orange, Ventura and San Diego counties.

An examination of coroners' records found that:

In 1,762 of those cases — 47%— drugs for which the deceased had a prescription were the sole cause or a contributing cause of death.

A small cadre of doctors was associated with a disproportionate number of those fatal overdoses. Seventy-one — 0.1% of all practicing doctors in the four counties — wrote prescriptions for drugs that caused or contributed to 298 deaths. That is 17% of the total linked to doctors' prescriptions.





Read More..